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Canon LIDE scanners are CIS

Canon LIDE scanners are CIS sensor based scanners, so they don't have a place outside of document scanning. That's why it's the only scanner tested that could't pick up the depth of the original and has banding artifacts. The CIS sensors are very shallow and ore only usefull for single page scanning. It's not a problem of LED which is the source of light, not the sensor. You can use LED lighting with CCD sensors with no problem.
The EPSON DS50000 is capable of 16bit/colour which translates into the 48bit/RGB. Unfortunately the included software only outputs normal 8bit (24bit/RGB) which is the real bummer.
As a final note, if you scan artwork and need accurate colour and details like paper texture, you need to invest in a colour calibration package with scanner support, or at least pay attention to scanner settings and options. Don't expect the auto corrention or presets to give you the best results.